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Does subpopulation size matter?

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Hi,
I've been analyzing the survey which is General Social Survey (n=23,093) in Canada. While I'm interested in a small subpopulation (n=214), I'm wondering if I can use this small subpopulation for logistic regressions. Since I could apply survey weights which make the subpopulation representing about 260,000, I thought it would be okay to use it. However, I now want to make sure of it.
Thank you for your help in advance.

Raphael from Edmonton, AB

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